Aptamers are nucleic acid ligands which exhibit specific binding to a desired target. Oligonucleotides are limited in their ability to form hydrophobic interactions. The affinity of aptamers can be improved with the introduction of hydrophobic modifiers into the structure of nitrogenous bases. https://cosmeticssquadets.shop/product-category/electrical-muscle-stimulators/
The Validation and Amplification of Random DNA Libraries with Modified Nucleobases for Click-SELEX
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