Invertebrates rely on innate immunity. including humoral and cellular immunity. to resist pathogenic infection. Previous studies showed that forkhead box transcription factor O (FOXO) participates in mucosal immune responses of mammals and the gut humoral immune regulation of invertebrates. https://www.roneverhart.com/Air-Jordan-12-Retro-Nubuck-GS-Black-White-University-Blue-153265-018/